The territory now occupied by the Monte Sacro district appears to have been inhabited since very ancient times. Some fossil remains dating back 120,000 years have been found here. The neighborhood arose in 1920 with a design that kept in mind the experience of English city gardens, in fact calling itself Aniene Garden City.

Worth visiting is the Church of the Holy Guardian Angels at the Garden City, built in the twentieth century in the Baroque style. The church faces Simplon Square and is in the transitional style between the late 16th and early 17th centuries with a slightly convex facade and an elegant window in place of the rose window under the gable. On the facade is the inscription “Angelis Custodibus.”

A must-see is the Nomentano Bridge, by which the Nomentana Street crosses the Aniene River. It is a Roman-era building of which the central archway from the 1st century is preserved, the upper part elevated and fortified in the Middle Ages. According to tradition, the meeting between Charlemagne and Leo III took place here in the year 800. Stendhal visited it on April 18, 1828, and speaks of the beauty of the place and the excellent Italian coffee.The bridge has been portrayed by painters, artists, and photographers because of its distinctive and gloomy appearance and the majesty of the main arch over which the turreted and crenellated medieval-era complex rises.

The Monte Sacro neighborhood is the birthplace of singer Claudio Baglioni; Sabina Guzzanti, comic and satirical actress, lived there; singer-songwriter Rino Gaetano and screenwriter Ennio Flaiano, famous for the films Guardie e Ladri, La Romana, Fantasmi a Roma and for collaborating with Fellini in the films I Vitelloni, La Dolce Vita, Otto e Mezzo”